KVP 10mg

KPV (Lys-Pro-Val) is a synthetic tripeptide (three amino acids: Lysine-Proline-Valine; molecular formula: C₁₆H₃₀N₄O₄; molecular weight ≈342.43 g/mol) representing the C-terminal active fragment of alpha-melanocyte-stimulating hormone (α-MSH), a naturally occurring peptide hormone involved in immune regulation and anti-inflammatory processes.
Key areas of research interest include:

• Potent anti-inflammatory effects through inhibition of key pathways such as NF-κB and MAPK signaling, leading to reduced production of pro-inflammatory cytokines (e.g., TNF-α) in cellular and animal model.
• Support for gastrointestinal health, including attenuation of colonic inflammation, preservation of mucosal integrity, acceleration of epithelial healing, and protection against barrier dysfunction in models of inflammatory bowel disease (IBD), ulcerative colitis, and related conditions.
• Promotion of wound healing and tissue repair, with observed benefits in dermal models for reducing inflammation in skin disorders (e.g., psoriasis, eczema, dermatitis) and enhancing recovery in various inflammatory states.
• Additional immunomodulatory and antimicrobial properties, including potential roles in systemic inflammation, immune balance, and protection against oxidative stress or immune-mediated damage across organ systems in preclinical studies.